If CEPA was indeed protecting public health, we would expect declining diseases from environmental exposures. Canadian examples point to the opposite. Endocrine-related obesity and metabolic syndrome, disorders of early development and sexual differentiation, and cancers in hormone-sensitive tissues have not been prevented. Endocrine disruption does not follow classic dose-response, so these substances must be regulated based on their innate hazard. With many thousands of EDCs, classes of similar chemicals require group actions.